COMMUNICATION on CONTEMPORARY ANTHROPOLOGY

Official journal of Shanghai Society of Anthropology eISSN1936-4458 pISSN1938-0580
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COM.on C.A.2:e2/11-16    Online published on Jul. 6, 2008.
REPORT
Evidence from Autosomal STR Data Supports a Central China Origin of Chao-Shan Population

XU Lina 1, FENG Guoying1, ZHOU Guangbiao1, HU Shengping1, 2

1.Center for Molecular Biology, 2.Forensic Genetics Laboratory, Shantou University Medical College, Shantou, Guangdong 515031 China

　

ABSTRACT: Chao-Shan people are typical Southern Han Chinese, and numbers of them emigrate to many other countries.The origin of Chao-Shan people is believed to be in Central China.The comparative study of the genetic polymorphism of Henan and Chao-Shan populations can test the hypothesis of Central China origin of Chao-Shan people at the genomic level. Here we performed a combined method of fluorescence labeled PCR and capillary electrophoresis to study the genetic polymorphism of 15 STR loci in 200 unrelated healthy individuals in Henan Han population. Combining our published STR allele frequency data and the new data from additional samples in Chao-Shan population and STR data of other populations in different areas obtained from peer-reviewed journals, we calculated the Nei’s genetic distance D’ between the populations with the PHYLIP software. The neighbor-joining phylogenetic tree was constructed based on the obtained Nei’s genetic distance to reveal population affinities and the Central China origin of Chao-Shan people. A total of 142 alleles and 451 genotypes were detected in Henan population. No deviation from Hardy-Weinberg equilibrium was observed in STR loci except for D3S1358. The phylogenic tree based on CODIS STR allele frequencies showed that Chao-Shan Han was much closer to Minnan Han, and relatively closer to Henan Han. Admixture analysis indicated that Chao-Shan Han and Minnan Han have similar proportional contributions from the Central China Han and the proportion was greater than 60%. Distinction between north and south populations in China was noticeable in the phylogenic tree. The 15 STR loci studied have potential usefulness for parental testing and forensic personal identification in Henan population. Our study showed the genetic similarity sustained by Chao-Shan Han and Minnan Han, and a pronounced Central China Han ancestry on the gene pools of the two groups.

Key words: Population genetics; Short tandem repeat (STR); Chao-Shan population; Henan population; Polymerase chain reaction (PCR)

　

Recieved: May.23, 2008  Accepted: Jun. 30,2008  Corresponding: sphu@stu.edu.cn

Full text:[PDF]
　

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